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The Hippo pathway in disease and therapy: cancer and beyond

The Hippo tumour suppressor pathway co-ordinates cell proliferation, cell death and cell differentiation to regulate tissue growth control. In mammals, a conserved core Hippo signalling module receives signal inputs on different levels to ensure the proper regulation of YAP/TAZ activities as transcr...

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Detalles Bibliográficos
Autores principales: Gomez, Marta, Gomez, Valenti, Hergovich, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107774/
https://www.ncbi.nlm.nih.gov/pubmed/25097725
http://dx.doi.org/10.1186/2001-1326-3-22