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Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity
Adenosine triphosphate (ATP) synthase β, the catalytic subunit of mitochondrial complex V, synthesizes ATP. We show that ATP synthase β is deacetylated by a human nicotinamide adenine dinucleotide (NAD(+))–dependent protein deacetylase, sirtuin 3, and its Drosophila melanogaster homologue, dSirt2. d...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107778/ https://www.ncbi.nlm.nih.gov/pubmed/25023514 http://dx.doi.org/10.1083/jcb.201404118 |