Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity

Adenosine triphosphate (ATP) synthase β, the catalytic subunit of mitochondrial complex V, synthesizes ATP. We show that ATP synthase β is deacetylated by a human nicotinamide adenine dinucleotide (NAD(+))–dependent protein deacetylase, sirtuin 3, and its Drosophila melanogaster homologue, dSirt2. d...

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Detalles Bibliográficos
Autores principales: Rahman, Motiur, Nirala, Niraj K., Singh, Alka, Zhu, Lihua Julie, Taguchi, Kaori, Bamba, Takeshi, Fukusaki, Eiichiro, Shaw, Leslie M., Lambright, David G., Acharya, Jairaj K., Acharya, Usha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107778/
https://www.ncbi.nlm.nih.gov/pubmed/25023514
http://dx.doi.org/10.1083/jcb.201404118

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