Excess centrosomes disrupt endothelial cell migration via centrosome scattering

Supernumerary centrosomes contribute to spindle defects and aneuploidy at mitosis, but the effects of excess centrosomes during interphase are poorly understood. In this paper, we show that interphase endothelial cells with even one extra centrosome exhibit a cascade of defects, resulting in disrupt...

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Detalles Bibliográficos
Autores principales: Kushner, Erich J., Ferro, Luke S., Liu, Jie-Yu, Durrant, Jessica R., Rogers, Stephen L., Dudley, Andrew C., Bautch, Victoria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107782/
https://www.ncbi.nlm.nih.gov/pubmed/25049273
http://dx.doi.org/10.1083/jcb.201311013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107782/
https://www.ncbi.nlm.nih.gov/pubmed/25049273
http://dx.doi.org/10.1083/jcb.201311013

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