Cargando…

Direct kinetochore–spindle pole connections are not required for chromosome segregation

Segregation of genetic material occurs when chromosomes move to opposite spindle poles during mitosis. This movement depends on K-fibers, specialized microtubule (MT) bundles attached to the chromosomes′ kinetochores. A long-standing assumption is that continuous K-fibers connect every kinetochore t...

Descripción completa

Detalles Bibliográficos
Autores principales: Sikirzhytski, Vitali, Magidson, Valentin, Steinman, Jonathan B., He, Jie, Le Berre, Maël, Tikhonenko, Irina, Ault, Jeffrey G., McEwen, Bruce F., Chen, James K., Sui, Haixin, Piel, Matthieu, Kapoor, Tarun M., Khodjakov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107786/
https://www.ncbi.nlm.nih.gov/pubmed/25023516
http://dx.doi.org/10.1083/jcb.201401090