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Direct kinetochore–spindle pole connections are not required for chromosome segregation
Segregation of genetic material occurs when chromosomes move to opposite spindle poles during mitosis. This movement depends on K-fibers, specialized microtubule (MT) bundles attached to the chromosomes′ kinetochores. A long-standing assumption is that continuous K-fibers connect every kinetochore t...
Autores principales: | Sikirzhytski, Vitali, Magidson, Valentin, Steinman, Jonathan B., He, Jie, Le Berre, Maël, Tikhonenko, Irina, Ault, Jeffrey G., McEwen, Bruce F., Chen, James K., Sui, Haixin, Piel, Matthieu, Kapoor, Tarun M., Khodjakov, Alexey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107786/ https://www.ncbi.nlm.nih.gov/pubmed/25023516 http://dx.doi.org/10.1083/jcb.201401090 |
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