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The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation

Organisms have evolved elaborate mechanisms to adjust intracellular nutrient levels in response to fluctuating availability of exogenous nutrients. During starvation, cells can enhance amino acid uptake and synthesis through the general amino acid control (GAAC) pathway, whereas nonessential cellula...

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Detalles Bibliográficos
Autores principales: Chen, Rui, Zou, Yilong, Mao, Dongxue, Sun, Daxiao, Gao, Guanguang, Shi, Jingwen, Liu, Xiaoqing, Zhu, Chen, Yang, Mingyu, Ye, Wanlu, Hao, Qianqian, Li, Ruiqiang, Yu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107793/
https://www.ncbi.nlm.nih.gov/pubmed/25049270
http://dx.doi.org/10.1083/jcb.201403009