Discovery of Fused Triazolo-thiadiazoles as Inhibitors of TNF-alpha: Pharmacophore Hybridization for Treatment of Neuropathic Pain

INTRODUCTION: Neuropathic pain is a complex, chronic pain state that is usually accompanied by tissue injury. With neuropathic pain, the nerve fibers themselves may be damaged, dysfunctional, or injured. METHODS: A series of pharmacophoric hybrids of substituted aryl semicarbazides incorporated into...

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Detalles Bibliográficos
Autores principales: Sharma, Monika, Deekshith, Vanamala, Semwal, Arvind, Sriram, Dharmarajan, Yogeeswari, Perumal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare Communications 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107862/
https://www.ncbi.nlm.nih.gov/pubmed/25134932
http://dx.doi.org/10.1007/s40122-012-0003-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107862/
https://www.ncbi.nlm.nih.gov/pubmed/25134932
http://dx.doi.org/10.1007/s40122-012-0003-6

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