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Novel Cul3 binding proteins function to remodel E3 ligase complexes

BACKGROUND: Cullins belong to a family of scaffold proteins that assemble multi-subunit ubiquitin ligase complexes to recruit protein substrates for ubiquitination via unique sets of substrate adaptor, such as Skp1 or Elongin B, and a substrate-binding protein with a conserved protein-protein intera...

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Detalles Bibliográficos
Autores principales: Wimuttisuk, Wananit, West, Mark, Davidge, Brittney, Yu, Kebing, Salomon, Arthur, Singer, Jeffrey D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107866/
https://www.ncbi.nlm.nih.gov/pubmed/25011449
http://dx.doi.org/10.1186/1471-2121-15-28