Diverse modes of binding in structures of Leishmania major N-myristoyltransferase with selective inhibitors

The leishmaniases are a spectrum of global diseases of poverty associated with immune dysfunction and are the cause of high morbidity. Despite the long history of these diseases, no effective vaccine is available and the currently used drugs are variously compromised by moderate efficacy, complex si...

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Detalles Bibliográficos
Autores principales: Brannigan, James A., Roberts, Shirley M., Bell, Andrew S., Hutton, Jennie A., Hodgkinson, Michael R., Tate, Edward W., Leatherbarrow, Robin J., Smith, Deborah F., Wilkinson, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107925/
https://www.ncbi.nlm.nih.gov/pubmed/25075346
http://dx.doi.org/10.1107/S2052252514013001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107925/
https://www.ncbi.nlm.nih.gov/pubmed/25075346
http://dx.doi.org/10.1107/S2052252514013001

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