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Diverse modes of binding in structures of Leishmania major N-myristoyltransferase with selective inhibitors
The leishmaniases are a spectrum of global diseases of poverty associated with immune dysfunction and are the cause of high morbidity. Despite the long history of these diseases, no effective vaccine is available and the currently used drugs are variously compromised by moderate efficacy, complex si...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107925/ https://www.ncbi.nlm.nih.gov/pubmed/25075346 http://dx.doi.org/10.1107/S2052252514013001 |