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The Potential for Transition Metal-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

Modulations of the potentially toxic transition metals iron (Fe) and copper (Cu) are implicated in the neurodegenerative process in a variety of human disease states including amyotrophic lateral sclerosis (ALS). However, the precise role played by these metals is still very much unclear, despite co...

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Detalles Bibliográficos
Autores principales: Lovejoy, David B., Guillemin, Gilles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107949/
https://www.ncbi.nlm.nih.gov/pubmed/25100994
http://dx.doi.org/10.3389/fnagi.2014.00173