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Role of the microtubule-targeting drug vinflunine on cell-cell adhesions in bladder epithelial tumour cells

BACKGROUND: Vinflunine (VFL) is a microtubule-targeting drug that suppresses microtubule dynamics, showing anti-metastatic properties both in vitro and in living cancer cells. An increasing body of evidence underlines the influence of the microtubules dynamics on the cadherin-dependent cell-cell adh...

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Detalles Bibliográficos
Autores principales: Aparicio, Luis A, Castosa, Raquel, Haz-Conde, Mar, Rodríguez, Marta, Blanco, Moisés, Valladares, Manuel, Figueroa, Angélica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107965/
https://www.ncbi.nlm.nih.gov/pubmed/25012153
http://dx.doi.org/10.1186/1471-2407-14-507