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Turnover of protein phosphorylation evolving under stabilizing selection

Most proteins are regulated by posttranslational modifications and changes in these modifications contribute to evolutionary changes as well as to human diseases. Phosphorylation of serines, threonines, and tyrosines are the most common modifications identified to date in eukaryotic proteomes. While...

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Detalles Bibliográficos
Autores principales: Landry, Christian R., Freschi, Luca, Zarin, Taraneh, Moses, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107968/
https://www.ncbi.nlm.nih.gov/pubmed/25101120
http://dx.doi.org/10.3389/fgene.2014.00245