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Sample size calculations in pediatric clinical trials conducted in an ICU: a systematic review

At the design stage of a clinical trial, several assumptions have to be made. These usually include guesses about parameters that are not of direct interest but must be accounted for in the analysis of the treatment effect and also in the sample size calculation (nuisance parameters, e.g. the standa...

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Detalles Bibliográficos
Autores principales: Nikolakopoulos, Stavros, Roes, Kit C B, van der Lee, Johanna H, van der Tweel, Ingeborg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107993/
https://www.ncbi.nlm.nih.gov/pubmed/25004909
http://dx.doi.org/10.1186/1745-6215-15-274