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Sample size calculations in pediatric clinical trials conducted in an ICU: a systematic review
At the design stage of a clinical trial, several assumptions have to be made. These usually include guesses about parameters that are not of direct interest but must be accounted for in the analysis of the treatment effect and also in the sample size calculation (nuisance parameters, e.g. the standa...
Autores principales: | Nikolakopoulos, Stavros, Roes, Kit C B, van der Lee, Johanna H, van der Tweel, Ingeborg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107993/ https://www.ncbi.nlm.nih.gov/pubmed/25004909 http://dx.doi.org/10.1186/1745-6215-15-274 |
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