Argonaute 2 promotes myeloma angiogenesis via microRNA dysregulation

BACKGROUND: Dysregulated microRNA (miRNA) expression contributes to cancer cell proliferation, apoptosis and angiogenesis. Angiogenesis is a hallmark of multiple myeloma (MM) development and progression. Argonaute 2 (AGO2) protein, a core component of the RNA-induced silencing complex (RISC), can di...

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Detalles Bibliográficos
Autores principales: Wu, Shuang, Yu, Wenjun, Qu, Xiaoyan, Wang, Rong, Xu, Ji, Zhang, Qiguo, Xu, Jiaren, Li, Jianyong, Chen, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108130/
https://www.ncbi.nlm.nih.gov/pubmed/24886719
http://dx.doi.org/10.1186/1756-8722-7-40