Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia

BACKGROUND: The pathological hallmark of multiple sclerosis (MS) is myelin phagocytosis. It remains unclear why microglia and macrophages demyelinate axons in MS, but previously found or yet-unknown changes in the myelin of MS patients could contribute to this process. We therefore studied whether m...

Descripción completa

Detalles Bibliográficos
Autores principales: Hendrickx, Debbie AE, Schuurman, Karianne G, van Draanen, Michael, Hamann, Jörg, Huitinga, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108133/
https://www.ncbi.nlm.nih.gov/pubmed/24684721
http://dx.doi.org/10.1186/1742-2094-11-64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108133/
https://www.ncbi.nlm.nih.gov/pubmed/24684721
http://dx.doi.org/10.1186/1742-2094-11-64

Ejemplares similares