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Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia
BACKGROUND: The pathological hallmark of multiple sclerosis (MS) is myelin phagocytosis. It remains unclear why microglia and macrophages demyelinate axons in MS, but previously found or yet-unknown changes in the myelin of MS patients could contribute to this process. We therefore studied whether m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108133/ https://www.ncbi.nlm.nih.gov/pubmed/24684721 http://dx.doi.org/10.1186/1742-2094-11-64 |