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Recruiting a Silent Partner for Activation of the Protein Kinase SRPK1

[Image: see text] The SRPK family of protein kinases regulates mRNA splicing by phosphorylating an essential group of factors known as SR proteins, so named for a C-terminal domain enriched in arginine–serine dipeptide repeats (RS domains). SRPKs phosphorylate RS domains at numerous sites altering S...

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Detalles Bibliográficos
Autores principales: Aubol, Brandon E., Adams, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108178/
https://www.ncbi.nlm.nih.gov/pubmed/24984036
http://dx.doi.org/10.1021/bi500483m