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Biosynthesis of a Central Intermediate in Hydrogen Sulfide Metabolism by a Novel Human Sulfurtransferase and Its Yeast Ortholog

[Image: see text] Human sulfide:quinone oxidoreductase (SQOR) catalyzes the conversion of H(2)S to thiosulfate, the first step in mammalian H(2)S metabolism. SQOR’s inability to produce the glutathione persulfide (GSS(–)) substrate for sulfur dioxygenase (SDO) suggested that a thiosulfate:glutathion...

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Detalles Bibliográficos
Autores principales: Melideo, Scott L., Jackson, Michael R., Jorns, Marilyn Schuman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108183/
https://www.ncbi.nlm.nih.gov/pubmed/24981631
http://dx.doi.org/10.1021/bi500650h