Fumagillin Prodrug Nanotherapy Suppresses Macrophage Inflammatory Response via Endothelial Nitric Oxide

[Image: see text] Antiangiogenesis has been extensively explored for the treatment of a variety of cancers and certain inflammatory processes. Fumagillin, a mycotoxin produced by Aspergillus fumigatus that binds methionine aminopeptidase 2 (MetAP-2), is a potent antiangiogenic agent. Native fumagill...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Hui-fang, Yan, Huimin, Hu, Ying, Springer, Luke E., Yang, Xiaoxia, Wickline, Samuel A., Pan, Dipanjan, Lanza, Gregory M., Pham, Christine T. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108210/
https://www.ncbi.nlm.nih.gov/pubmed/24941020
http://dx.doi.org/10.1021/nn502372n

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108210/
https://www.ncbi.nlm.nih.gov/pubmed/24941020
http://dx.doi.org/10.1021/nn502372n

Ejemplares similares