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Dose-dependent regulation of cell proliferation and collagen degradation by estradiol on ligamentum flavum

BACKGROUND: Estradiol plays an important role in the regulation of collagen metabolism. Deficiency of estradiol has been reported to be associated with the degeneration of many connective tissues. However, the association of estradiol and hypertrophy of the ligamentum flavum was seldom explored. The...

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Detalles Bibliográficos
Autores principales: Chen, Mei-Hsiu, Hu, Chao-Kai, Chen, Pei-Ru, Chen, Yu-Shan, Sun, Jui-Sheng, Chen, Ming-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108226/
https://www.ncbi.nlm.nih.gov/pubmed/25022571
http://dx.doi.org/10.1186/1471-2474-15-238