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Environment-responsive Nanophores for Therapy and Treatment Monitoring via Molecular MRI Quenching

The effective delivery of therapeutics to disease sites significantly contributes to drug efficacy, toxicity and clearance. Here we demonstrate that clinically approved iron oxide nanoparticles (Ferumoxytol) can be utilized to carry one or multiple drugs. These so called ‘nanophores’ retain their ca...

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Detalles Bibliográficos
Autores principales: Kaittanis, Charalambos, Shaffer, Travis M., Ogirala, Anuja, Santra, Santimukul, Perez, J. Manuel, Chiosis, Gabriela, Li, Yueming, Josephson, Lee, Grimm, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108301/
https://www.ncbi.nlm.nih.gov/pubmed/24594970
http://dx.doi.org/10.1038/ncomms4384