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Strategic Focus on 3R Principles Reveals Major Reductions in the Use of Animals in Pharmaceutical Toxicity Testing

The principles of the 3Rs, Replacement, Reduction and Refinement, are being increasingly incorporated into legislations, guidelines and practice of animal experiments in order to safeguard animal welfare. In the present study we have studied the systematic application of 3R principles to toxicologic...

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Detalles Bibliográficos
Autores principales: Törnqvist, Elin, Annas, Anita, Granath, Britta, Jalkesten, Elisabeth, Cotgreave, Ian, Öberg, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108312/
https://www.ncbi.nlm.nih.gov/pubmed/25054864
http://dx.doi.org/10.1371/journal.pone.0101638