Generation of Neutralizing Monoclonal Antibodies against a Conformational Epitope of Human Adenovirus Type 7 (HAdv-7) Incorporated in Capsid Encoded in a HAdv-3-Based Vector

The generation of monoclonal antibodies (MAbs) by epitope-based immunization is difficult because the immunogenicity of simple peptides is poor and T cells must be potently stimulated and immunological memory elicited. A strategy in which antigen is incorporated into the adenoviral capsid protein ha...

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Detalles Bibliográficos
Autores principales: Liu, Minglong, Tian, Xingui, Li, Xiao, Zhou, Zhichao, Li, Chenyang, Zhou, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108376/
https://www.ncbi.nlm.nih.gov/pubmed/25054273
http://dx.doi.org/10.1371/journal.pone.0103058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108376/
https://www.ncbi.nlm.nih.gov/pubmed/25054273
http://dx.doi.org/10.1371/journal.pone.0103058

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