Sensory Neurons Do Not Induce Motor Neuron Loss in a Human Stem Cell Model of Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is an autosomal recessive disorder leading to paralysis and early death due to reduced SMN protein. It is unclear why there is such a profound motor neuron loss, but recent evidence from fly and mouse studies indicate that cells comprising the whole sensory-motor circui...

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Detalles Bibliográficos
Autores principales: Schwab, Andrew J., Ebert, Allison D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108398/
https://www.ncbi.nlm.nih.gov/pubmed/25054590
http://dx.doi.org/10.1371/journal.pone.0103112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108398/
https://www.ncbi.nlm.nih.gov/pubmed/25054590
http://dx.doi.org/10.1371/journal.pone.0103112

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