PIK3CA Gene Mutations and Overexpression: Implications for Prognostic Biomarker and Therapeutic Target in Chinese Esophageal Squamous Cell Carcinoma

AIMS: To evaluate PIK3CA gene mutations and PIK3CA expression status in Chinese esophageal squamous cell carcinoma (ESCC) patients, and their correlation with clinicopathological characteristics and clinical outcomes. METHODS: Direct sequencing was applied to investigate mutations in exons 9 and 20...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lin, Shan, Ling, Zhang, Shaokai, Ying, Jianming, Xue, Liyan, Yuan, Yanling, Xie, Yongqiang, Lu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108430/
https://www.ncbi.nlm.nih.gov/pubmed/25054828
http://dx.doi.org/10.1371/journal.pone.0103021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108430/
https://www.ncbi.nlm.nih.gov/pubmed/25054828
http://dx.doi.org/10.1371/journal.pone.0103021

Ejemplares similares