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Hormesis in cancer immunology: Does the quantity of an immune reactant matter?
We recently reported that tumor-directed antibodies could either stimulate, or inhibit, tumor progression, dependent upon the dosage used. The narrow range over which this immune response curve (IRC) occurs is surprising. Here we discuss features of the IRC, the mechanisms identified so far, and the...
Autores principales: | Pearce, Oliver MT, Läubli, Heinz, Bui, Jack, Varki, Ajit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108457/ https://www.ncbi.nlm.nih.gov/pubmed/25083340 http://dx.doi.org/10.4161/onci.29312 |
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