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A novel preclinical murine model of immune-mediated metastatic dormancy

The mechanisms underlying cancer dormancy are poorly understood. We have developed a preclinical murine model in which immunosurveillance restrains spontaneous metastases in permanent dormancy. The model faithfully recapitulates human metastatic dormancy and may be useful to decipher the immune mech...

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Detalles Bibliográficos
Autores principales: Romero, Irene, Garrido, Federico, Garcia-Lora, Angel M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108459/
https://www.ncbi.nlm.nih.gov/pubmed/25083338
http://dx.doi.org/10.4161/onci.29258