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‘Hardcore’ OX40(+) immunosuppressive regulatory T cells in hepatic cirrhosis and cancer

Human regulatory T cells (Tregs) comprise an array of distinct subsets displaying diverse functions in response to microenvironmental signals. Here, we review our recent findings demonstrating the preferential accumulation of uncommitted, Th1-like and OX40(-) Tregs in non-cirrhotic tissues in contra...

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Detalles Bibliográficos
Autores principales: Piconese, Silvia, Timperi, Eleonora, Barnaba, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108463/
https://www.ncbi.nlm.nih.gov/pubmed/25083337
http://dx.doi.org/10.4161/onci.29257