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Immune cells in pancreatic cancer: Joining the dark side

Pancreatic tumors are rich in immune cell infiltrates that include CD4(+) T-cell subsets encompassing both regulatory T cells and T(H)17 cells. Rather than protecting the organism by exerting an anticancer effect, these T-cell subsets promote tumor formation. Thus, re-activation of antitumor immunit...

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Detalles Bibliográficos
Autores principales: Zhang, Yaqing, McAllister, Florencia, Pasca di Magliano, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108467/
https://www.ncbi.nlm.nih.gov/pubmed/25083330
http://dx.doi.org/10.4161/onci.29125