Characterization of a Novel BCHE “Silent” Allele: Point Mutation (p.Val204Asp) Causes Loss of Activity and Prolonged Apnea with Suxamethonium

Butyrylcholinesterase deficiency is characterized by prolonged apnea after the use of muscle relaxants (suxamethonium or mivacurium) in patients who have mutations in the BCHE gene. Here, we report a case of prolonged neuromuscular block after administration of suxamethonium leading to the discovery...

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Detalles Bibliográficos
Autores principales: Delacour, Herve, Lushchekina, Sofya, Mabboux, Isabelle, Bousquet, Aurore, Ceppa, Franck, Schopfer, Lawrence M., Lockridge, Oksana, Masson, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108472/
https://www.ncbi.nlm.nih.gov/pubmed/25054547
http://dx.doi.org/10.1371/journal.pone.0101552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108472/
https://www.ncbi.nlm.nih.gov/pubmed/25054547
http://dx.doi.org/10.1371/journal.pone.0101552

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