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Renaturing Membrane Proteins in the Lipid Cubic Phase, a Nanoporous Membrane Mimetic

Membrane proteins play vital roles in the life of the cell and are important therapeutic targets. Producing them in large quantities, pure and fully functional is a major challenge. Many promising projects end when intractable aggregates or precipitates form. Here we show how such unfolded aggregate...

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Detalles Bibliográficos
Autores principales: Li, Dianfan, Caffrey, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108929/
https://www.ncbi.nlm.nih.gov/pubmed/25055873
http://dx.doi.org/10.1038/srep05806