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Renaturing Membrane Proteins in the Lipid Cubic Phase, a Nanoporous Membrane Mimetic
Membrane proteins play vital roles in the life of the cell and are important therapeutic targets. Producing them in large quantities, pure and fully functional is a major challenge. Many promising projects end when intractable aggregates or precipitates form. Here we show how such unfolded aggregate...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108929/ https://www.ncbi.nlm.nih.gov/pubmed/25055873 http://dx.doi.org/10.1038/srep05806 |