Reprogramming ovarian and breast cancer cells into non-cancerous cells by low-dose metformin or SN-38 through FOXO3 activation

Cancer is a leading cause of death worldwide. Because the cytotoxic effects of conventional chemotherapies often harm normal tissue cells along with cancer cells, conventional chemotherapies cause many unwanted or intolerable side effects. Thus, there is an unmet medical need to establish a paradigm...

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Detalles Bibliográficos
Autores principales: Hu, Theodore, Chung, Young Min, Guan, Michelle, Ma, Michael, Ma, Jessica, Berek, Jonathan S., Hu, Mickey C-T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108946/
https://www.ncbi.nlm.nih.gov/pubmed/25056111
http://dx.doi.org/10.1038/srep05810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108946/
https://www.ncbi.nlm.nih.gov/pubmed/25056111
http://dx.doi.org/10.1038/srep05810

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