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Decipher the dynamic coordination between enzymatic activity and structural modulation at focal adhesions in living cells

Focal adhesions (FAs) are dynamic subcellular structures crucial for cell adhesion, migration and differentiation. It remains an enigma how enzymatic activities in these local complexes regulate their structural remodeling in live cells. Utilizing biosensors based on fluorescence resonance energy tr...

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Detalles Bibliográficos
Autores principales: Lu, Shaoying, Seong, Jihye, Wang, Yi, Chang, Shiou-chi, Eichorst, John Paul, Ouyang, Mingxing, Li, Julie Y.-S., Chien, Shu, Wang, Yingxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108961/
https://www.ncbi.nlm.nih.gov/pubmed/25056908
http://dx.doi.org/10.1038/srep05756