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Treatment of acute lung injury by targeting MG53-mediated cell membrane repair

Injury to lung epithelial cells has a role in multiple lung diseases. We previously identified mitsugumin 53 (MG53) as a component of the cell membrane repair machinery in striated muscle cells. Here we show that MG53 also has a physiological role in the lung and may be used as a treatment in animal...

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Detalles Bibliográficos
Autores principales: Jia, Yanlin, Chen, Ken, Lin, Peihui, Lieber, Gissela, Nishi, Miyuki, Yan, Rosalie, Wang, Zhen, Yao, Yonggang, Li, Yu, Whitson, Bryan A., Duann, Pu, Li, Haichang, Zhou, Xinyu, Zhu, Hua, Takeshima, Hiroshi, Hunter, John C., McLeod, Robbie L., Weisleder, Noah, Zeng, Chunyu, Ma, Jianjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109002/
https://www.ncbi.nlm.nih.gov/pubmed/25034454
http://dx.doi.org/10.1038/ncomms5387