The influence of different cellular environments on PET radioligand binding: An application to D(2/3)-dopamine receptor imaging

Various D(2/3) receptor PET radioligands are sensitive to endogenous dopamine release in vivo. The Occupancy Model is generally used to interpret changes in binding observed in in vivo competition binding studies; an Internalisation Hypothesis may also contribute to these changes in signal. Extensio...

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Detalles Bibliográficos
Autores principales: Quelch, Darren R., Withey, Sarah L., Nutt, David J., Tyacke, Robin J., Parker, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109028/
https://www.ncbi.nlm.nih.gov/pubmed/24910074
http://dx.doi.org/10.1016/j.neuropharm.2014.05.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109028/
https://www.ncbi.nlm.nih.gov/pubmed/24910074
http://dx.doi.org/10.1016/j.neuropharm.2014.05.040

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