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Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

Recent advances in genomic research have revealed the existence of a large number of transcripts devoid of protein-coding potential in multiple organisms (1-8). While the functional role for long non-coding RNAs (lncRNAs) has been best defined in epigenetic phenomena such as X inactivation and impri...

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Detalles Bibliográficos
Autores principales: Lai, Fan, Orom, Ulf A, Cesaroni, Matteo, Beringer, Malte, Taatjes, Dylan J, Blobel, Gerd A., Shiekhattar, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109059/
https://www.ncbi.nlm.nih.gov/pubmed/23417068
http://dx.doi.org/10.1038/nature11884