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Regulated proteolysis of the alternative sigma factor SigX in Streptococcus mutans: implication in the escape from competence
BACKGROUND: SigX (σ(X)), the alternative sigma factor of Streptococcus mutans, is the key regulator for transcriptional activation of late competence genes essential for taking up exogenous DNA. Recent studies reveal that adaptor protein MecA and the protease ClpC act as negative regulators of compe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109385/ https://www.ncbi.nlm.nih.gov/pubmed/25005884 http://dx.doi.org/10.1186/1471-2180-14-183 |