Cargando…

Regulated proteolysis of the alternative sigma factor SigX in Streptococcus mutans: implication in the escape from competence

BACKGROUND: SigX (σ(X)), the alternative sigma factor of Streptococcus mutans, is the key regulator for transcriptional activation of late competence genes essential for taking up exogenous DNA. Recent studies reveal that adaptor protein MecA and the protease ClpC act as negative regulators of compe...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Gaofeng, Tian, Xiao-Lin, Gomez, Zubelda A, Li, Yung-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109385/
https://www.ncbi.nlm.nih.gov/pubmed/25005884
http://dx.doi.org/10.1186/1471-2180-14-183