Multi-electrode array study of neuronal cultures expressing nicotinic β2-V287L subunits, linked to autosomal dominant nocturnal frontal lobe epilepsy. An in vitro model of spontaneous epilepsy

Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a partial sleep-related epilepsy which can be caused by mutant neuronal nicotinic acetylcholine receptors (nAChR). We applied multi-electrode array (MEA) recording methods to study the spontaneous firing activity of neocortical cultures...

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Detalles Bibliográficos
Autores principales: Gullo, Francesca, Manfredi, Irene, Lecchi, Marzia, Casari, Giorgio, Wanke, Enzo, Becchetti, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109561/
https://www.ncbi.nlm.nih.gov/pubmed/25104926
http://dx.doi.org/10.3389/fncir.2014.00087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109561/
https://www.ncbi.nlm.nih.gov/pubmed/25104926
http://dx.doi.org/10.3389/fncir.2014.00087

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