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Multi-electrode array study of neuronal cultures expressing nicotinic β2-V287L subunits, linked to autosomal dominant nocturnal frontal lobe epilepsy. An in vitro model of spontaneous epilepsy
Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a partial sleep-related epilepsy which can be caused by mutant neuronal nicotinic acetylcholine receptors (nAChR). We applied multi-electrode array (MEA) recording methods to study the spontaneous firing activity of neocortical cultures...
Autores principales: | Gullo, Francesca, Manfredi, Irene, Lecchi, Marzia, Casari, Giorgio, Wanke, Enzo, Becchetti, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109561/ https://www.ncbi.nlm.nih.gov/pubmed/25104926 http://dx.doi.org/10.3389/fncir.2014.00087 |
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