Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence

Hepatic glucose phosphorylation by GK (glucokinase) is regulated by GKRP (GK regulatory protein). GKRP forms a cytosolic complex with GK followed by nuclear import and storage, leading to inhibition of GK activity. This process is initiated by low glucose, but reversed nutritionally by high glucose...

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Detalles Bibliográficos
Autores principales: Zelent, Bogumil, Raimondo, Anne, Barrett, Amy, Buettger, Carol W., Chen, Pan, Gloyn, Anna L., Matschinsky, Franz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109836/
https://www.ncbi.nlm.nih.gov/pubmed/24568320
http://dx.doi.org/10.1042/BJ20131363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109836/
https://www.ncbi.nlm.nih.gov/pubmed/24568320
http://dx.doi.org/10.1042/BJ20131363

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