Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1β(MYPT1) phosphatase complex and the SCF(βTrCP) E3 ubiquitin ligase

NUAK1 (NUAK family SnF1-like kinase-1) and NUAK2 protein kinases are activated by the LKB1 tumour suppressor and have been implicated in regulating multiple processes such as cell survival, senescence, adhesion and polarity. In the present paper we present evidence that expression of NUAK1 is contro...

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Detalles Bibliográficos
Autores principales: Banerjee, Sourav, Zagórska, Anna, Deak, Maria, Campbell, David G., Prescott, Alan R., Alessi, Dario R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109838/
https://www.ncbi.nlm.nih.gov/pubmed/24785407
http://dx.doi.org/10.1042/BJ20140408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109838/
https://www.ncbi.nlm.nih.gov/pubmed/24785407
http://dx.doi.org/10.1042/BJ20140408

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