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Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1β(MYPT1) phosphatase complex and the SCF(βTrCP) E3 ubiquitin ligase
NUAK1 (NUAK family SnF1-like kinase-1) and NUAK2 protein kinases are activated by the LKB1 tumour suppressor and have been implicated in regulating multiple processes such as cell survival, senescence, adhesion and polarity. In the present paper we present evidence that expression of NUAK1 is contro...
Autores principales: | Banerjee, Sourav, Zagórska, Anna, Deak, Maria, Campbell, David G., Prescott, Alan R., Alessi, Dario R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109838/ https://www.ncbi.nlm.nih.gov/pubmed/24785407 http://dx.doi.org/10.1042/BJ20140408 |
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