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Fibrin binds to collagen and provides a bridge for αVβ3 integrin-dependent contraction of collagen gels

The functional significance of fibrin deposits typically seen in inflammatory lesions, carcinomas and in healing wounds is not fully understood. In the present study, we demonstrate that fibrinogen/fibrin specifically bound to native Col I (collagen type I) and used the Col I fibre network as a base...

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Detalles Bibliográficos
Autores principales: Reyhani, Vahid, Seddigh, Pegah, Guss, Bengt, Gustafsson, Renata, Rask, Lars, Rubin, Kristofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109839/
https://www.ncbi.nlm.nih.gov/pubmed/24840544
http://dx.doi.org/10.1042/BJ20140201