Silencing Is Noisy: Population and Cell Level Noise in Telomere-Adjacent Genes Is Dependent on Telomere Position and Sir2

Cell-to-cell gene expression noise is thought to be an important mechanism for generating phenotypic diversity. Furthermore, telomeric regions are major sites for gene amplification, which is thought to drive genetic diversity. Here we found that individual subtelomeric TLO genes exhibit increased v...

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Detalles Bibliográficos
Autores principales: Anderson, Matthew Z., Gerstein, Aleeza C., Wigen, Lauren, Baller, Joshua A., Berman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109849/
https://www.ncbi.nlm.nih.gov/pubmed/25057900
http://dx.doi.org/10.1371/journal.pgen.1004436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109849/
https://www.ncbi.nlm.nih.gov/pubmed/25057900
http://dx.doi.org/10.1371/journal.pgen.1004436

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