Cargando…
iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections
Identifying master regulators of biological processes and mapping their downstream gene networks are key challenges in systems biology. We developed a computational method, called iRegulon, to reverse-engineer the transcriptional regulatory network underlying a co-expressed gene set using cis-regula...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109854/ https://www.ncbi.nlm.nih.gov/pubmed/25058159 http://dx.doi.org/10.1371/journal.pcbi.1003731 |