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An Essential Nonredundant Role for Mycobacterial DnaK in Native Protein Folding

Protein chaperones are essential in all domains of life to prevent and resolve protein misfolding during translation and proteotoxic stress. HSP70 family chaperones, including E. coli DnaK, function in stress induced protein refolding and degradation, but are dispensable for cellular viability due t...

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Detalles Bibliográficos
Autores principales: Fay, Allison, Glickman, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109909/
https://www.ncbi.nlm.nih.gov/pubmed/25058675
http://dx.doi.org/10.1371/journal.pgen.1004516