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An Essential Nonredundant Role for Mycobacterial DnaK in Native Protein Folding
Protein chaperones are essential in all domains of life to prevent and resolve protein misfolding during translation and proteotoxic stress. HSP70 family chaperones, including E. coli DnaK, function in stress induced protein refolding and degradation, but are dispensable for cellular viability due t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109909/ https://www.ncbi.nlm.nih.gov/pubmed/25058675 http://dx.doi.org/10.1371/journal.pgen.1004516 |